The DualShock 2, Xbox 360 controller, and numerous more gamepads are among the numerous controllers that PCSX2 supports. Users can then customize their emulation experience to match their hardware capabilities and personal preferences. To improve the visual appeal of games, players can change the aspect ratio and resolution, turn on anisotropic and anti-aliasing filtering, and apply custom shaders. PCSX2 offers a multitude of customization options in addition to compatibility. Most games, including some of the most well-known ones like Grand Theft Auto: San Andreas, Final Fantasy X, and Kingdom Hearts II, may be played on the emulator. The great degree of compatibility with a variety of PS2 games is one of PCSX2's distinguishing characteristics.

An active user base and contributor base for the open-source emulator ensures frequent updates and a broad variety of support. It enables users to utilize their own controller or keyboard to play their favorite PS2 games on a computer. A very well-liked and frequently used Playstation 2 emulator for the PC is PCSX2.